Fullmetal Alchemist Manga vs First TV Series - ROUND FOUR
In the original manga, Edward is "rescued" by the homonuculi from Laboratory 5 after sustaining injuries in the fight with the Slicer Brothers and given into military custody. In first animated television series, however, the homunuculi attempt to get Edward to use the red water and live prisoners to transmute a Philosopher's Stone. This is the beginning of some of the bigger differences between the anime and the source material.
Chapter 13: Fullmetal Body
Event(s): Ed is confronted by the homonuculi, who kill the Slicer brothers, and knock him out, then destroy the laboratory. Ed is brought into military custody by Ross and Brosch.
Episode 21: The Red Glow/Episode 22: Created Human